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Data on the efficacy and safety of adjuvant. The mutation is a gene rearrangement These gene rearrangements lead to constitutive activation of the alk kinase and subsequent alk driven tumor formation.
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Alectinib targets cancer cells that have specific changes, called rearrangements, in the alk gene We aim to describe initial and subsequent treatments used, survival outcomes, prognostic. The molecular pathogenesis, clinical features, and treatment of nsclc associated with the alk fusion oncogene are discussed here