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In hemodynamically stable patients with pe, treatment with single bolus tenecteplase is feasible at the same dosages used for acute myocardial infarction and is associated with reduction of rvd at 24 hours. Is now the first controlled trial to demonstrate the feasibility of tenecteplase treatment in (normotensive) patients with acute pe. Abstract pulmonary embolism (pe) is a serious and prevalent cause of vascular disease

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Nevertheless, optimal treatment for many phenotypes of pe remains uncertain Following a number of case reports and small series, the study of becattini et al Treating pe requires appropriate risk stratification as a first step.

Our study shows that tenecteplase is very effective and safe in the treatment of pe with minimal risk of bleeding in high risk group and intermediate risk and even in selective low risk category group of patients.

To assess the efficacy and safety of tenecteplase in patients with pulmonary embolism (pe) We completed the literature search on may 31, 2021 using pubmed, embase and the web of science