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To evaluate the impact of prehospital treatment with epinephrine (epi), antihistamines (ah), and/or corticosteroids (cs) on anaphylaxis management. Corticosteroids and antihistamines more often than epinephrine for suspected anaphylaxis Exposure to a known causative agent increases the index of suspicion
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Some patients can have idiopathic anaphylaxis, so the absence of a trigger doesn't exclude anaphylaxis The objective of this study was determine if the use of epinephrine, corticosteroids or antihistamines affect rates of biphasic reactions in patients presenting to the emergency department (ed) with anaphylaxis. Having two organ systems involved strongly supports the diagnosis.
After reviewing the published evidence, the authors state that the use of corticosteroids has no role in the acute management of anaphylaxis.
This guideline is for healthcare providers who are expected to treat anaphylaxis during their usual clinical role (e.g Use of corticosteroids in anaphylaxis The rate of corticosteroid use in emergency treatment of anaphylaxis varied from 48% to 100% with an average of 67.99%. Antihistamines have no role in treating or preventing respiratory or cardiovascular symptoms of anaphylaxis
Do not use oral sedating antihistamines as side effects (drowsiness or lethargy) may mimic some signs of anaphylaxis. Patients with frequent idiopathic anaphylaxis may benefit from daily antihistamine therapy (both h 1 antagonists and h 2 antagonists) or, in rare circumstances, daily corticosteroid therapy. Cetirizine) in preference to chlorphenamine which causes sedation steroids in anaphylaxis (1) routine use of corticosteroids to treat anaphylaxis is not advised consider giving steroids after initial resuscitation for refractory reactions or ongoing asthma/shock.
