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It has the characteristics of high sensitivity, widely effective linear range, high homogeneity, high reproducibility, minimal matrix effect, good stability and high detection throughput. Instead of testing one sample at a time, hts uses robotics and smart software to do the heavy lifting, helping researchers Find active compounds (like potential new drugs or better. However, most high throughput assays were not developed to specifically support 3d systems
Here, we describe the need for improved compatibility and relevant advances toward deployment and adoption of high throughput 3d models to improve disease modeling, drug efficacy testing, and precision medicine applications. Hts is gaining attention from pharmaceuticals and biotechnology companies for accelerating their drug discovery programs Conventional drug discovery program is time consuming and expensive A drug candidate must first be proven safe before entering clinical trials